Hospital Infrastructure

Montreal Heart Institute (MHI) is a highly-specialized fully integrated academic hospital and leading research center with the expertise and facilities to conduct early phase clinical research.
This includes Phase I, first-in-human and proof-of-concept studies, both in healthy volunteers and patients.

• Drug studies (including new chemical entities and natural health products), diagnostics and medical devices;
• Access to specific patient populations such as patients with cardiovascular or metabolic diseases;
• 20-bed short-stay unit with specialized medical and nursing staff and 24/7 care including emergencies;
• Laboratory and central imaging services: echocardiography, ultrasound, Cardiac Magnetic Resonance (CMR) and CT scans;
• Supervision and operational services: central management, monitoring, data management, statistical analysis and reporting that meet regulatory standards and Good Clinical Practice (GCP).

The Montreal Heart Institute’s Core Laboratories are internationally recognized in image acquisition, central readings and data analysis. The MHI Core Laboratories acts as a central resource for technique development, standardization and dissemination (training regarding specific techniques), quality assurance for image acquisition, as well as handling and central analysis of imaging data collected in all imaging sites of our worldwide network.

The MHI Core Laboratories use cutting edge imaging solutions and have dedicated staff bringing years of experience in the interpretation of medical images. The MHI Core Laboratories work under good clinical practices and have extensive written and validated standard operating procedures (including independent image assessments) ensuring consistency and reproducibility of measurements, and compliance to protocols and regulations.

Each of the MHI's central laboratories is headed by an experienced cardiologist, radiologist or nuclear medicine specialist. The services offered include the following:
• Echocardiography
• Cardiovascular nuclear medicine (PET and SPECT)
• Electrocardiography (ECG) + Holter
• Intravascular Ultrasound (IVUS)
• Quantitative Coronary Angiography (QCA)
• Coronary computed tomography angiogram (Coronary CTA)
• Carotid Intima-Media Thickness (cIMT)
• Magnetic Resonance Imaging (MRI)
• Optical Coherence Tomograpy (OCT)
• Cardiovascular Biomarkers
• Pharmacogenomics