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Medical Imaging Network


CAIN (Canadian Atherosclerosis Imaging Network) is a pan-Canadian imaging network funded through grants from the Canadian Foundation for Innovation (CFI) and the Canadian Institutes of Health Research (CIHR).
This unique research network is focused on the pathobiology of atherosclerotic disease as it pertains to the coronary and carotid circulations. The CAIN research program involves the creation of a unique national network focused on in vivo imaging of vessel wall disease, combined with imaging of occult end-organ disease as well as the acquisition of clinical and pathological endpoints.
CAIN enables unprecedented cross-sectional and longitudinal clinical studies of patients with atherosclerotic disease in coronary or carotid vascular beds, and has established an international resource for studying the natural history, progression, regression and novel therapeutic interventions aimed at atherosclerosis.

Vascular imaging expertise and infrastructure in all major Canadian cities are linked in this novel multidisciplinary team to form a core clinical research network; patients are recruited from qualified sites across the country to enable unique research into the vascular biology of atherosclerosis, imaging technology assessment and clinical vascular imaging.
The project leaders, co-Principal Investigators, core and recruitment sites represent Canada’s leading atherosclerosis imaging experts, spanning coronary and carotid territories and embodying both basic imaging science and clinical imaging research.

The CAIN infrastructure allows worldwide study sites to de-identify and transmit, via secure internet connection, medical images to the Montreal Health Innovations Coordinating Center. The MHICC DICOM repository manages the distribution of image data to core laboratories located at the Montreal Heart Institute and at CAIN partner institutions.


A national research network, MITNEC (Medical Imaging Trial NEtwork of Canada) was created at the MHI to address the objectives of moving innovations in medical imaging toward their broad application in clinical research and facilitating the uptake of research outcomes into clinical practice and improved patient care.
It is truly national in scope with participation from 14 universities located in 4 provinces across Canada (the 5 above plus the University of British Columbia, Queens Elizabeth II Health Science Center, Montreal Neurological Institute, Thunder Bay Regional Health Sciences Centre, Lawson Health Research Institute, Cross Cancer Institute, Université Laval, Centre Hospitalier Universitaire de Sherbrooke, McMaster University).
Again, the MHICC plays the role of the sole coordinating centre and repository for this network.